Stainless Steel Aseptic Pharmaceutical Split Butterfly AB Valve
Grade: Manufactured from high-quality AISI 316L or AISI 304 stainless steel, offering excellent corrosion resistance, high mechanical strength, and full compatibility with sterile pharmaceutical processing environments.
Standard: Conforms to DIN, SMS, ISO, 3A, and ASME BPE sanitary standards, ensuring reliable quality and hygienic performance.
Working Pressure: Maximum working pressure of 0.6 MPa (6 bar), suitable for contained powder transfer between vessels, isolators and process equipment.
Temperature Range: -20℃ to +150℃, suitable for CIP online cleaning and SIP online sterilization processes.
PTFE Seals: Standard PTFE seals provide excellent chemical resistance, low friction coefficient, and broad temperature adaptability, ensuring stable and long-lasting sealing performance.
EPDM / Silicone Seals: Optional EPDM and pharmaceutical-grade Silicone seals are available for applications requiring enhanced temperature flexibility and FDA compliance.
Application: Sterile and contained powder transfer in pharmaceutical, biotechnology, food and fine chemical industries.
The aseptic split butterfly AB valve, also known as the Alpha-Beta valve, is a hygienic contained-transfer valve widely used in industries such as pharmaceutical, biotechnology, food, dairy, and fine chemical industries.It is mainly used for sterile powder and granule transfer between vessels, isolators, reactors, IBC drums and process equipment.The AB valve is manufactured from high-quality 316L or 304 sanitary stainless steel and designed and produced according to DIN, SMS, ISO, 3A and ASME BPE standards. The valve separates into an active half and a passive half, and each half carries its own disc, so the product remains fully enclosed during connection, transfer and disconnection.The sealing faces are precisely machined and electro-polished. The smooth surface design eliminates dead corners, effectively prevents medium residue and cross-contamination, and meets the requirements of high-containment sterile transfer systems.The equipment can be used together with isolators, reactors, tablet presses, freeze dryers and IBC drum systems. It also supports CIP (Clean-In-Place) online cleaning and SIP (Sterilization-In-Place) online sterilization, making it widely applicable in various sterile automated production systems.
Ouraseptic split butterfly AB valve has significant advantages over conventional butterfly valves and open charging methods in terms of containment performance, operator protection, contamination control and batch safety.
Compared with ordinary (open-type) butterfly valves:
- No product exposure to the atmosphere during transfer;
- No dust emission into the working area;
- Operators are protected from potent or toxic powders.
Compared with open charging and manual powder dumping:
- Eliminates cross-contamination between batches;
- Meets GMP containment and hygiene requirements;
- Supports reproducible, documented transfer processes.
Compared with other contained transfer systems:
- Simpler structure and lower investment cost;
- Quick docking, locking and undocking;
- Compatible with existing vessels, isolators and IBC drums.
Accessories
- Active Valve Body: Precisely manufactured using AISI 316L sanitary stainless steel.
- Passive Valve Body: Precisely manufactured using AISI 316L sanitary stainless steel.
- Split Butterfly Discs (Active + Passive): AISI 316L with electro-polished sealing faces.
- Valve Stem / Drive Shaft: AISI 316L stainless steel.
- Handle / Actuator Bracket: AISI 304 stainless steel.
- Docking Ring / Quick-Locking Clamp: Made of sanitary stainless steel and treated with mirror polishing.
- Sealing Elements: PTFE / FKM / EPDM / Silicone, FDA compliant, designed to match sanitary sealing structures.
- Connection Ends: Tri-clamp, PN6/PN10 flange, ANSI #150.
- Size Range: DN50~DN300
- Working Pressure: 0~6 Bar
- Working Temperature: -20°C~150°C
- Material:304, 304L, 316L
- Surface Finish: Electro-polished, Ra ≤ 0.4 μm optional
- Connection Type: Tri-clamp / Flange / ANSI; Standards: DIN (German), SMS (Swedish), 3A (American), ISO (international); Size range: 2″–12″
- Certification Grade：FDA compliant seals, ASME BPE compatible
- Applicable Medium: Pharmaceutical powders, APIs, sterile granules, food-grade and fine chemical powders
Digital advantages
- 1. CNC Machining - Manufactured using high-precision CNC equipment to ensure dimensional consistency.
- 2. Electro-Polishing Technology - Provides stable and uniform surface roughness control.
- 3. ASME BPE / DIN Standard Manufacturing - Strictly manufactured according to international sanitary standards.
- 4. Full-Process Quality Inspection - Material inspection;Dimensional inspection;Pressure inspection;Surface inspection.
- 5. Flexible Customization Capability - Supports project customization and development of non-standard sizes and connections.
- Contained Transfer Design
- F: The active and passive halves keep the powder fully enclosed during docking, transfer and separation.
- A:No product or dust escapes at any stage of the transfer process.
- B: Protects both the operator and the product, and keeps the working area clean.
- Independent Dual-Disc Sealing
- F: Each half carries its own disc and seals separately after transfer.
- A: Prevents cross-contamination between batches and residual powder exposure.
- B: Guarantees batch integrity and simplifies process validation.
- 316L Sanitary Stainless Steel Construction
- F: Manufactured from AISI 316L with electro-polished wetted surfaces.
- A:High corrosion resistance and long service life in CIP/SIP environments.
- B: Extends equipment life and reduces maintenance costs.
- Multiple Seal Options
- F: PTFE, FKM, EPDM and pharmaceutical-grade Silicone seals are available.
- A: Matches media, temperature and FDA compliance requirements.
- B: One valve platform covers different processes and reduces spare parts.
- Flexible Connection Compatibility
- F: Tri-clamp, flange and ANSI ends can be combined freely.
- A: Fits existing vessels, isolators and IBC drums without modification.
- B: Simplifies system integration and reduces installation costs.
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